B12 may be injected into a muscle or under the skin at 100 mcg daily for a week, every other day for another week, and then every three or four days for a month
While the NIH does not specify a tolerable upper intake level for vitamin B12, a study published in the JAMA Network Open found that high intakes of vitamin B12, such as from daily supplementation of 25 micrograms or higher, increased the risk of bone fracture [3] [4]
A marked colour change in the reconstituted solution may indicate degradation
Contraindications Known hypersensitivity to any component of the formula
More preliminary findings, documented but less consistently replicated: FAK-paxillin pathway: Research has identified activation of the focal adhesion kinase (FAK) and paxillin signalling pathway, involved in cell migration and tissue organisation in laboratory models
Available from: Vitamin B-12 and depression: Are they related